Two Premier League teams battling for Europe lock horns on Wednesday night as eighth-placed Manchester United play host to sixth-placed Newcastle United at Old Trafford.
Chelsea, another top-six hopeful, are also in action away against Brighton & Hove Albion, while there are other fixtures taking place in La Liga, Ligue 1, Scottish Premiership, Coppa Italia, MLS and Women's Super League.
Below is Sports Mole's selection of predictions and previews for today's and tomorrow's fixtures.